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Lariam Legal Claims and Lawsuits
Lariam Side Effects
Lariam History: Story of Problems
FDA Warnings and Label Changes
Lariam's more common side effects include: nausea, vomiting, diarrhea, abdominal pain, loss of balance dizziness, vertigo, sleep disorders, ringing in the ears, headache, muscle cramps, abnormal dreams, emotional instability, insomnia, panic attacks, hallucinations, anxiety, depression, paranoid reactions, convulsions, visual impairment, numbness, rashes, and itching. The use of Lariam with quinine or quinidine may result in cardiac arrest. There have been approximately a dozen reported suicides and hundreds of cases of depression among Lariam users. Furthermore, it is believed there may be links between an outbreak of domestic killings at Fort Bragg North Carolina linked to Lariam.
In 1999, Roche USA advised against prescribing Lariam for patients with "active depression or with a history of psychosis or convulsions". Roche "officially" warned that possible adverse reactions included: vomiting, dizziness, syncope, extrasystoles, myalgia, nausea, fever, headache, chills, diarrhea, skin rash, abdominal pain, fatigue, loss of appetite, tinnitus, bradycardia, hair loss, emotional problems, pruritus, asthenia, transient emotional disturbances, telogen effluvium (loss of resting hair), seizures, cardiopulmonary arrest, encephalopathy, circulatory disturbances (hypotension, hypertension, flushing, syncope), tachycardia or palpitation, bradycardia, irregular pulse, extrasystoles, exanthema, erythema, urticaria, pruritus, muscle weakness, muscle cramps, myalgia, arthralgia, and malaise.
According to Roche U.S.A., Lariam is not recommended for anyone
with epilepsy, who is pregnant, for scuba divers, or for anyone
who has a history of psychological problems or depression.
The FDA is investigating 600 reports of adverse reactions. Half the reports mentioned a psychiatric side effect, among reported side effects, thirteen suicidal thoughts, four attempted suicides, and one suicide death.